Official Newsletter of South Africans for the abolition of VIVISECTION, Proudly hosted by

Issue 16
MRC Baboons
Vet Council Continues to obfuscate
Local researchers question animal models
Does Dove give a Rats's *** ?
Proposed Code a 'Vivisector's Charter'
Who'll move the cheese ?
Enchantrix - now country-wide distribution
Vivisection retards medical progress
The compassionate Consumer
Dr Vernon's Casebook
Regulars
Editorial
Science Cafe
Hall of Fame
Top Quotes
Archives


LOCAL RESEARCHERS QUESTION USE OF ANIMALS IN RESEARCH


      Various medical researchers, also in South Africa, have now questioned the fallacious use of animal models to study essentially human diseases, e.g. Alzheimer's, AIDS, etc.
      In response to scientists' excitement over the reaction of monkeys injected with an AIDS vaccine similar to that which was due to be tested in South Africa soon, Prof. Salim Abdool Karim, deputy vice-chancellor of the University of Natal and co-chair of the protocol committee overseeing the AIDS vaccine initiative, said: "While the response is exciting, we cannot extrapolate the findings to humans as monkeys and humans have different immune responses."
      Dr. Koos Smit, a former medical researcher who, for 28 years at the Wits Medical School, was involved in 1000 liver and kidney transplants using primates as experimental models, is of the opinion that "in retrospect the application of this research was not of much use."
      Dr. James A. Temlett, of the neurology unit of the University of the Witwatersrand Medical School in South Africa, stated: "Acute parkinsonism models (animal models) have limitations when compared with chronic disease states, and caution should be present when comparing parkinsonism data with human disease. (Animal Models) do not reflect the complexities of the human basal ganglion." (Current Opinion in Neurology 1996;9:303-7)



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